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US 4,301,166 AGranted
Hydroxyethyl-azole compounds, their production and their medicinal use
AssigneeBayer Aktiengesellschaft
InventorsErik Regel, Karl H. Buchel, Ingo Haller, Manfred Plempel
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Abstract
The invention relates to hydroxyethyl-azole compounds and methods for their preparation. Also included in the invention are compositions containing said hydroxyethyl-azole compounds and methods for the use of said compounds and compositions as antimycotic agents.
Claims11
A hydroxyethyl-azole of the formula ##STR147## or a salt thereof in which
- Az represents imidazol-1-yl, 1,2,4-triazol-1-yl or 1,2,4-triazol-4-yl,
- R denotes optionally substituted phenyl, naphthyl or tetrahydronaphthyl which is unsubstituted or substituted by halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy or halogenoalkyl with 1 to 4 carbon atoms and up to 5 halogen atoms,
- R.sup.1 represents phenyl which is unsubstituted or substituted by halogen or C.sub.1 -C.sub.4 -alkyl and
- R.sup.2 represents hydrogen, or
- R.sup.1 and R.sup.2 together, in the o-position relative to one another, represent an optionally halogen or C.sub.1 -C.sub.4 -alkyl substituted methylene bridge with 3 to 5 methylene groups, or, together with the phenyl ring, represent naphthyl,
- R.sup.3 represents halogen, an alkyl, or alkoxy group with in each case 1 to 4 carbon atoms or halogenoalkyl with 1 to 4 carbon atoms and up to 5 halogen atoms and
- n is 0, 1, 2 or 3.
4 more elements
Dependencies are inferred from the claim text.