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US 4,301,152 AGranted
Immunologic adjuvant
AssigneeMerck & Co., Inc.
InventorMitree M. Ponpipom
Life of this patent
Estimating the term…
Abstract
Immunologic adjuvants are obtained by the synthesis of 6-(5-cholesten-3.beta.-yloxy)hexyl 6-amino-6-deoxy-1-thio-.beta.-D-galactopyranoside and its 6-deoxy-6-oleamido derivative.
Claims9
An intermediate in the preparation of 6-(5-cholesten-3.beta.-yloxy)hexyl 6-amino-6-deoxy-1-thio-.beta.-D-galactopyranoside selected from the group consisting of 1,2,3,4-tetra-O-acetyl-6-deoxy-6-phthalimido-D-galactopyranose;
- 2,3,4-tri-O-acetyl-6-deoxy-6-phthalimido-.alpha.-D-galactopyranosyl bromide;
- 2,3,4-tri-O-acetyl-6-deoxy-6-phthalimido-1-thio-.beta.-D-galactopyranose;
- or 6-(5-cholesten-3.beta.-yloxy)hexyl 2,3,4-tri-O-acetyl-6-deoxy-6-phthalimido-1-thio-.beta.-D-galactopyranoside .
An immunologic adjuvant compound selected from 6-(5-cholesten-3.beta.-yloxy)hexyl 6-amino-6-deoxy-1-thio-.beta.-D-galactopyranoside and the corresponding oleic acid amide thereof.
Dependencies are inferred from the claim text.