Red blood cell labelling kit
AssigneeMerck & Co., Inc.
InventorPaul-Emile Bonneau
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Abstract
This invention relates to a method for efficiently labelling red blood cells , which permits the imaging of blood pools in the intact animal or human patient, accomplished by injection of a saline solution of an alkaline earth metal salt of glucoheptonic acid and a non-toxic stannous salt followed by injection with a solution of sodium pertechnetate Tc 99 m to tag the red blood cells. The invention also relates to the kit used in the method of our invention consisting of a single vial containing 25 mg. calcium glucoheptonate and 3 mg. of stannous chloride dihydrate in 2 ml. of saline solution.
Claims4
A method of imaging blood pools in patients suspected of having cardiovascular abnormalities which comprises the steps of
- (1) intravenous injection of a solution comprising a water soluble, non-toxic, pharmaceutically acceptable salt of ketoglucoheptonic acid and a water soluble, non-toxic stannous salt;
- (2) waiting a period of 30 minutes;
- and
- (3) intravenous injection of a sterile saline solution containing from 2-20 mCi of sodium pertechnetate-Tc99m.
Dependencies are inferred from the claim text.