Method and apparatus for introducing samples to a mass spectrometer
AssigneeJapan Spectroscopic Co., Ltd.
InventorsTsugio Takeuchi, Shin Tsuge, Yukio Hirata, Koichi Mochizuki
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AssigneeJapan Spectroscopic Co., Ltd.
InventorsTsugio Takeuchi, Shin Tsuge, Yukio Hirata, Koichi Mochizuki
Estimating the term…
Simplified method and apparatus for connecting a liquid chromatograph, particularly of a high-performance type, directly to a mass spectrometer without using any complicated devices conventionally available, for the purpose of continuous and stable mass spectrometric measurement of a liquid sample, either liquid or solution, more commonly an effluent supplied directly from a column of the liquid chromatograph or an aliquot portion thereof extracted through a simple and ordinary splitter, or any other liquid samples prepared for the mass spectrometric analysis. Such a liquid sample is first sprayed into finely divided particles by a nebulizing means mainly consisting of a double-tubing capillary so that the sample is easily vaporized, and finally introduced into an ionizing portion of the mass spectrometer in continuous and stable manner.
A method for continuously introducing a large molecular weight compound in vapor and fine particle form to an ion source of a mass spectrometer which comprises:
An apparatus for continuously introducing a sample compound in vapor and fine particle form into an ion source of a mass spectrometer which includes:
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