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US 4,296,093 AGranted
Cyclic carboxamides having a physiological cooling effect
AssigneeWilkinson Sword Limited
InventorsDavid G. Rowsell, John M. Gascoyne, Roger Hems
Life of this patent
Estimating the term…
Abstract
Compositions are disclosed having a physiological cooling action on the skin. The compositions contain, as the active ingredient, alkyl-substituted cyclohexanamides.
Claims12
In a manufactured consumer product for application to or consumption by the human body and being:
- (a) a personal care product comprising a topically or orally administrable base medium containing a flavourant, colourant, perfume, surface active agent or antiseptic agent;
- (b) an ingestible preparation comprising an edible or potable base containing a flavourant or colourant.
- (c) a pharmaceutical preparation comprising a topically or orally administrable pharmaceutically acceptable carrier and an active pharmaceutical ingredient;
- or
- (d) a tobacco containing consumer product, said consumer product also containing an ingredient capable of stimulating the cold receptors of the nervous system of the surface tissues of the body when brought into contact therewith by application or consumption of the said product, the improvement which comprises using as said cold receptor stimulating ingredient an effective amount of a cyclic carboxamide of the formula ##STR5## wherein R' is C.sub.1 -C.sub.5 alkyl and R" is hydrogen or C.sub.1 -C.sub.5 alkyl, with the proviso that R' and R" together provide a total of from 1-8 carbon atoms;
- and
- R.sub.1 and R.sub.2 are each hydrogen, C.sub.1 -C.sub.5 alkyl or C.sub.1 -C.sub.8 hydroxyalkyl and together provide a total of 0 to 8 carbon atoms, with the proviso that when R.sub.1 is H then R.sub.2 may also be alkylcarboxyalkyl of up to 6 carbon atoms.
4 more elements
Dependencies are inferred from the claim text.