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US 4,292,425 AGranted
.beta.Galactosyl-umbelliferone valproic acid conjugates
AssigneeMiles Laboratories, Inc.
InventorsRobert T. Buckler, John F. Burd, Raphael C. Wong
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Abstract
Reagents for use in binding assays, particularly immunoassays, to determine valproic acid in liquid media such as serum. Such reagents include antibody to valproic acid and .beta.-galactosyl-umbelliferone-valproic acid conjugates. Also provided are compounds used to prepare such reagents, including valproic acid immunogen conjugates and intermediates in the synthesis of such immunogen conjugates and .beta.-galactosyl-umbelliferone-labeled conjugates.
Claims2
A .beta.-galactosyl-umbelliferone-valproic acid conjugate of the formula:
- ##STR6## wherein n is an integer from 3 through 8.
Dependencies are inferred from the claim text.