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US 4,291,121 AGranted
Bilirubin-resistant determination of uric acid and cholesterol
AssigneeMiles Laboratories, Inc.
InventorsGiancarlo Acquati, Giovanni Berti, Piero Fossati
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AssigneeMiles Laboratories, Inc.
InventorsGiancarlo Acquati, Giovanni Berti, Piero Fossati
Estimating the term…
A composition, test device, method of making a test device and process for bilirubin-resistant determination of an analyte selected from uric acid or cholesterol in a fluid sample are disclosed. More particularly, the composition is of the type comprising means responsive to the presence of the particular analyte to be determined in the sample, a phenol and 4-aminophenazone to which resistance to interference by bilirubin is imparted by inclusion therein of reagent means comprising a ferrocyanide ion. The uric acid or cholesterol responsive means is preferably of the type which determines peroxides formed from enzymatic conversion of the analyte. The composition can optionally be incorporated with a carrier to provide a test device.
Composition for the determination of an analyte selected from uric acid and cholesterol in a fluid sample of the type comprising means responsive to the presence of said analyte in said sample, a phenol or napthol and 4-aminophenazone wherein the improvement comprises reagent means comprising a ferrocyanide ion.
A composition for the determination of uric acid in a fluid sample of the type comprising means responsive to the presence of uric acid on the sample, unsubstituted phenol and 4-aminophenazone wherein the improvement comprises reagent means comprising potassium ferrocyanide.
A composition for the determination of cholesterol in a fluid sample of the type comprising means responsive to the presence of cholesterol in the sample, unsubstituted phenol and 4-aminophenazone wherein the improvement comprises reagent means comprising sodium ferrocyanide.
Dependencies are inferred from the claim text.