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AssigneeChinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
InventorsJozsef Knoll, Zoltan Meszaros, Istvan Hermecz, Ferenc Fulop, Gabor Bernath, Sandor Virag, Gabor Nagy, Peter Szentmiklosi
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Compounds of the formula ##STR1## or pharmaceutically acceptable acid-addition or quaternart ammonium salts thereof wherein R is hydroxy, carboxy, lower alkoxycarbonyl, benzyloxycarbonyl, phenoxycarbonyl, carbamoyl, N-loweralkyl-carbamoyl, N,N-dilower-alkyl-carbamoyl, carboazido, carbohydrazido or cyano; R.sup.2 is C.sub.1 to C.sub.6 alkyl; R.sup.3 is C.sub.1 to C.sub.6 alkyl or benzyl; and R.sup.4 is a single electron pair, hydrogen or lower alkyl; and the dotted lines represent saturated or unsaturated bonds, are disclosed with analgesic properties.
A compound of the formula ##STR10## or a pharmaceutically acceptable acid addition or quaternary ammonium salt thereof wherein
2-methyl-3-ethyl-8-ethoxycarbonyl-4-oxo-4H-pyrido(1,2-a)pyrimidine or a pharmaceutically acceptable acid addition or quaternary ammonium salt thereof.
An analgesic method of treatment which comprises the step of administering to an afflicted animal an analgesically effective amount of a compound of the formula ##STR11## or a pharmaceutically acceptable acid addition or quaternary ammonium salt thereof, wherein
Dependencies are inferred from the claim text.