Process for preparing .DELTA..sup.9(11) and/or .DELTA..sup.16 -unsaturated sternoids
AssigneeSchering Corporation
InventorsPaul-Eberhard Schulze, Ulrich Kerb
Life of this patent
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Abstract
A process for preparing a .DELTA..sup.9(11) - and/or .DELTA..sup.16 -unsaturated steroid comprises heating the corresponding steroid of the pregnane series substituted by 9.alpha.-chloro- and/or 16.alpha.-chloro- or 17.alpha.-acyloxy, in an inert, aprotic high-boiling solvent at 180.degree.-350.degree. C.
Claims10
A process for preparing a .DELTA..sup.9(11) -and/or .DELTA..sup.16 -unsaturated steroid of the pregnane series which consists essentially of heating the corresponding 9,11- and/or 16- saturated steroid substituted by 17.alpha.-acyloxy, 16.alpha.-chloro or 17.alpha.-acyloxy and 9.alpha.-chloro, in an inert, aprotic high-boiling solvent at 180.degree.-350.degree. C.
Dependencies are inferred from the claim text.