Fatty emulsion and process for the preparation thereof
AssigneeTanabe Seiyaku Co., Ltd.
InventorsKiyoshi Harada, Yoshiyuki Koida, Hiroshi Miura
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Abstract
A stable, oil-in-water type, fine particle, fatty emulsion which is regulated with a pH value regulator consisting of an organic amine and a buffer solution to a pH value of 6.0 to 8.0, said fatty emulsion having a fatty particle size of not larger than 2.mu.. The fatty emulsion can stably be kept for a long period of time without lowering of the pH value and aggregation of the fatty particles.
Claims24
A fatty emulsion comprising an oil-in-water type fatty emulsion which is regulated to a pH value of 6.0 to 8.0 with a pH value regulator consisting of a combination of at least one organic amine selected from the group consisting of lysine, arginine, ornithine, histidine, trishydroxymethylaminomethane and triethanolamine and at least one buffer solution selected from the group consisting of a potassium dihydrogen phosphate-dipotassium hydrogen phosphate buffer, potassium dihydrogen phosphate-disodium hydrogen phosphate, potassium dihydrogen phosphate-trisodium phosphate, sodium dihydrogen phosphate-disodium hydrogen phosphate, citric acid-disodium hydrogen phosphate, and tris-HCl.
A process for the preparation of a fatty emulsion which comprises emulsifying a vegetable oil into an aqueous dispersion of an emulsifying agent;
- adding to the resulting crude emulsion a pH value regulator consisting of at least one organic amine selected from the group consisting of lysine, arginine, ornithine, histidine, trishydroxymethylaminomethane and triethanolamine and at least one buffer selected from the group consisting of a phosphate buffer, a citric acid-phosphate buffer and tris-HCl buffer to regulate a pH value thereof to a pH range of 6.0 to 8.0;
- and emulsifying the mixture completely to give an oil-in-water fatty emulsion.
A process for the preparation of a fatty emulsion, which comprises emulsifying a vegetable oil into an aqueous dispersion of an emulsifying agent;
- emulsifying further the resulting crude emulsion to give an oil-in-water type fatty emulsion;
- and adding thereto a pH value regulator consisting of at least one organic amine selected from the group consisting of lysine, arginine, ornithine, histidine, trishydroxymethylaminomethane and triethanolamine and at least one buffer selected from the group consisting of a phosphate buffer, a citric acid-phosphate buffer and tris-HCl buffer to regulate a pH value thereof to a pH range of 6.0 to 8.0.
Dependencies are inferred from the claim text.