Method for production of acylhydrazones of formyl-acetic acid ester
AssigneeSchering Corporation
InventorHans-Rudolf Kruger
Life of this patent
Estimating the term…
Abstract
A process is provided for production of acylhydrazones of formyl-acetic acid ester of the general formula ##STR1## wherein R.sub.1 is an alkyl group with from 1 to 6 carbon atoms and R.sub.2 is an alkoxy group or an amino group. A propiolic acid ester of the general formula H--C.tbd.C--COOR.sub.1 is contacted with hydrazine derivatives of the general formula H.sub.2 N--NH--CO--R.sub.2 in the presence of a solvent such as water or a lower alcohol. The resulting products are technically valuable starting materials for the production of biocides, for example of 1,2,3-thiadiazole derivatives.
Claims10
A process for the production of acylhydrazones of formyl-acetic acid ester of the general formula ##STR4## wherein R.sub.1 is an alkyl group with from 1 to 6 carbon atoms and R.sub.2 is an alkoxy group or an amino group
- comprising
- contacting a propiolic acid ester of the general formula
- H--C.tbd.C--COOR.sub.1 (II)
- with hydrazine derivatives of the general formula
- H.sub.2 N--NH--CO--R.sub.2 (III)
- in the presence of a solvent.
Dependencies are inferred from the claim text.