2-Benzoyl-4-nitroanilides and their use as medicaments
AssigneePierre Fabre S.A.
InventorsHenri Cousse, Gilbert Mouzin
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AssigneePierre Fabre S.A.
InventorsHenri Cousse, Gilbert Mouzin
Estimating the term…
New derivatives of 2-benzoyl-4-nitro anilides, their preparation and their use as medicaments. The new chemical derivatives of the invention have the general formula ##STR1## in which R represents a linear or branched alkyl group, an alkenyl group, a cycloalkyl group or a benzyl group, R.sub.1 represents a hydrogen atom, an alkyl group or a hydroxy alkyl group, R.sub.2 represents a hydroxy-alkyl, alkenyl or alkynyl group, possibly substituted one or more times by an alkyl radical, or a cycloalkyl group having three to six carbon atoms; R.sub.1 and R.sub.2 may furthermore form, with the nitrogen atom to which they are attached, a nitrogen heterocycle containing possibly a second heteroatom selected from among oxygen and nitrogen; under the condition, however, that when R.sub.2 represents a hydroxy-alkyl group R.sub.1 may not be a hydrogen atom. Use as hypnotic agents for the treatment of insomnia.
2-benzoyl-4-nitro anilides having the formula I:
Dependencies are inferred from the claim text.