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US 4,289,763 AGranted
Novel corticoids, the preparation thereof and the use thereof
AssigneeSchering Corporation
InventorsHenry Laurent, Rudolf Wiechert, Hans Wendt, Joachim-Friedrich Kapp
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Abstract
Corticoids of the formula ##STR1## wherein X is fluorine, chlorine and R is hydrogen, C.sub.1-6 alkanoyl, benzoyl or --OCO--A--COOH wherein A is a carbon-to-carbon bond or a C.sub.1-6 hydrocarbon chain, or when R is --OCO--A--COOH, the physiologically acceptable salts thereof with a base, have high effectiveness, e.g., antiinflammatorily but with attendant low side effects.
Claims13
A corticoid of the formula ##STR5## wherein X is fluorine or chlorine and
- R is hydrogen, C.sub.1-6 alkanoyl, benzoyl or --OCO--A--COOH
- wherein
- A is a carbon-to-carbon bond or a C.sub.1-6 hydrocarbon chain,
- or when
- R is --OCO--A--COOH, the physiologically acceptable salts thereof with a base.
2 more elements
Dependencies are inferred from the claim text.