Polymeric diffusion matrix containing phenylpropanolamine
AssigneeKey Pharmaceuticals, Inc.
InventorsAlec D. Keith, Wallace Snipes
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Abstract
There is disclosed a polymeric diffusion matrix for the sustained release of phenylpropanolamine by transdermal delivery to a patient wherein the matrix comprises a polar plasticizer, polyvinylalcohol, polyvinylpyrrolidone, and a pharmaceutically effective amount of phenylpropanolamine.
Claims10
A self-supporting polymeric diffusion matrix for the sustained release of phenylpropanolamine in order to transdermally deliver said phenylpropanolamine to a patient and provide said patient with a bronchodilator and nasal decongestant effect, said matrix comprising from about 2 to about 60% of a polar plasticizer, from about 6 to about 20% by weight polyvinylalcohol, from about 2 to 10% by weight polyvinylpyrrolidone, and a pharmaceutically effective amount of phenylpropanolamine to provide a sustained release of said phenylpropanolamine over a prolonged period.
A method for the transdermal delivery of phenylpropanolamine to a patient to provide said patient with a bronchodilator and nasal decongestant effect, comprising applying to said patient a self-supporting diffusion matrix comprising from about 2 to about 60% by weight of a polar plasticizer, from about 6 to about 20% by weight polyvinylalcohol, from about 2 to about 10% by weight polyvinylpyrrolidone, and a pharmaceutically effective amount of phenylpropanolamine to provide a sustained release of said phenylpropanolamine over a prolonged period.
Dependencies are inferred from the claim text.