US 4,289,703 AGranted

Antibiotics

AssigneeBeecham Group Limited

InventorsKevin D. Barrow, Graham Mellows

Life of this patent

Estimating the term…

Abstract

An active antibacterial substance from Pseudomonas fluoroescens bacterium designated pseudominic acid and as a co-product a minor amount of a compound having an additional OH group designated as pseudomonic acid I. These two substances obtained are separated and purified. Alkali metal salts and methyl esters can be prepared. The antibacterial activity of pseudomonic acid appears to reside in the free acid form which results from in vivo hydrolysis of the methyl ester which is crystalline.

Claims1

Dependent claims

The methyl ester of pseudomonic acid I having the formula:

##STR5## and being in substantially pure form.

Dependencies are inferred from the claim text.

Facts

Application: 05/741,215Filed 12 Nov 1976 · continuation in part
Priority: GB 27653/7112 Jun 1971
Granted: 15 Sep 1981
Term ends: Not estimatedThe source records don’t support an estimate.

Classification9 codes

C07D 407/06
Containing two hetero rings: linked by a carbon chain containing only aliphatic carbon atoms
A61K 31/19
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids: carboxylic acids, e.g. valproic acid
A61P 31/04
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics: antibacterial agents
C07D 309/10
With hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals,…:…

Family

Serial261,042Parent of this division · filed 8 Jun 1972
Serial444,791Parent of this continuation · filed 22 Feb 1974
Serial612,237Parent of this continuation-in-part · filed 11 Sep 1975
US 4,289,703 AThis patent

From the US filing history. Foreign family members aren’t listed.

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