Process for the synthesis of 2,4-dinitro-6-t-butyl-3-methylanisole, referred to as musk ambrette
AssigneeSociete Nationale des Poudres et Explosifs
InventorsHelene M. Pascal, Jean-Marie L. Emeury
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Abstract
The invention relates to a process for the synthesis of 2,4-dinitro-6-t-butyl-3-methylanisole or musk ambrette. The process according to the invention is characterized in that 6-t-butyl-3-methylanisole is reacted with a nitrating mixture consisting of 30 to 50% of acetic acid, 20 to 30% of acetic anhydride and 25 to 45% by weight of nitric acid, at between 7.degree. and 15.degree. C. The product is recovered in the pure state with a good yield by adding small amounts of water to the crude reaction mixture. Application: Synthesis of a scented product.
Claims4
Process for the synthesis of 2,4-dinitro-6-t-butyl-3-methylanisole which consists of reacting 3-methyl-6-t-butylanisole with a ternary nitrating mixture which comprises acetic anhydride, acetic acid and nitric acid at between 5.degree. and 30.degree. C. wherein said nitrating mixture consists of a total of 30 to 50% by weight of acetic acid, 20 to 30% by weight of acetic anhydride and 25 to 45% by weight of nitric acid, and said 2,4-dinitro-6-t-butyl-3-methylanisole is recovered as a precipitate by introducing into the crude reaction mixture, preferably slowly and while stirring, one or more small amounts of water which are less than 100% by weight of the amount of nitrating mixture used.
Dependencies are inferred from the claim text.