Anti-ulcer treatment method
AssigneeJohn Wyeth & Brother Limited
InventorRoger Crossley
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Abstract
A method for treating ulcers or hypersecretion is described employing an anti-ulcer agent of formula I. Accordingly the invention provides a method for treating ulcers or hypersecretion in a mammal which comprises administering to said mammal an effective amount of an anti-ulcer agent of formula I ##STR1## wherein R is alkyl of 1 to 6 carbon atoms or aralkyl of 7 to 12 carbon atoms, R.sup.1 is hydrogen or alkyl of 1 to 6 carbon atoms, Z.sup.- is an anion selected from halide, lower alkyl- and arylsulphonate and the R and R.sup.1 radicals may be the same or different, and A represents a methylene or ethylene radical optionally substituted by alkyl of 1 to 6 carbon atoms, oxo or hydroxy and S is sulphur. Anti-ulcer compositions comprising a compound of formula I and a pharmaceutical carrier are also described.
Claims3
A method for treating ulcers or hypersecretion in a mammal which comprises orally administering to said mammal an effective amount of an anti-ulcer agent of formula I ##STR5## wherein R is alkyl of 1 to 6 carbon atoms, or aralkyl of 7-12 carbon atoms, R.sup.1 is hydrogen or alkyl of 1 to 6 carbon atoms, and the R and R.sup.1 radicals may be the same or different, A is methylene or ethylene radical, optionally substituted by lower alkyl of 1 to 6 carbon atoms, oxo, or hydroxy, S is sulphur and Z.sup.- is a halide or lower alkyl-or by aryl sulphonate anion.
Dependencies are inferred from the claim text.