Dithioacylproline derivatives

Abstract

Compounds having the formula ##STR1## wherein: R.sub.1 is hydrogen, alkyl, aryl or arylalkyl; R.sub.2 is hydrogen and R.sub.3 is hydrogen, hydroxy, alkoxy or halogen, or together R.sub.2 and R.sub.3 can be .dbd.O or --X--(CH.sub.2).sub.t --X-- wherein X is oxygen or sulfur and t is 2 or 3; R.sub.4 is hydrogen or alkyl; R.sub.5 is hydrogen, alkyl or trifluoromethyl; R.sub.6 is alkyl of 1 to 20 carbon atoms, aryl, arylalkyl or a 5- or 6-membered heterocyclic group having 1 or 2 nitrogen, sulfur or oxygen atoms in the ring; R.sub.7 is aryl; m is 0, 1 or 2; and n is 1 or 2 have useful hypotensive activity.

Dependencies are inferred from the claim text.