Halogen derivatives of 8-hydroxycarboxylic acids; the processes for their preparation and medicaments in which they are present
AssigneeLaboratoires Hoechst S.A.
InventorsPierre Simon, Jacques Dreux
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Abstract
Halogen derivatives of 8-hydroxycarboxylic acids, which correspond to the formula ##STR1## (open form, in a basic medium) or to the formula ##STR2## (cyclized form, in an acid medium) in which formulae: X.sub.1 and X.sub.2 are halogen atoms, n.sub.1 and n.sub.2 are integers between 0 and 5, but, if n.sub.1 =0, n.sub.2 is different from 0, and vice versa, R is a hydrogen atom or an alkyl or aryl group, and Cation represents an ion originating from a base, or a metal ion, which is pharmaceutically compatible are suitable as antidepressants having a psychostimulant action.
Claims6
A compound of the formula ##STR37## wherein X.sub.1 and X.sub.2 are chlorine atoms, n.sub.1 and n.sub.2 are integers between 0 and 5, but, if n.sub.1 =O, n.sub.2 is different from O, and vice versa, R is hydrogen, alkyl or aryl and Cation represents a pharmaceutically acceptable cation.
A compound of the formula ##STR38## wherein X.sub.1 and X.sub.2 are chlorine atoms, n.sub.1 and n.sub.2 are integers between 0 and 5, but, if n.sub.1 =O, n.sub.2 is different from O, and vice versa, and R is hydrogen, aklyl or aryl.
Dependencies are inferred from the claim text.