Complexes of bivalent copper
OwnerBarry Boettcher, William R. Walker +1inventors
InventorsBarry Boettcher, William R. Walker, Michael W. Whitehouse
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Abstract
Compositions containing neural copper complexes, particularly copper-salicylate complexes having the formula Cu[C.sub.6 H.sub.4 (X)COO].sub.2. Y in which Y represents dimethylsulfoxide, dimethylformamide or an alkanol and in which X is preferably --OH, together with a pharmaceutically acceptable, non-aqueous carrier have been found to have therapeutic activity in the treatment of inflammatory diseases. The compositions have been found particularly suitable for the treatment of arthritis.
Claims19
A topical anti-inflammatory therapeutic composition comprising an anti-inflammatory effective amount of a neutral copper complex of the formula Cu[C.sub.6 H.sub.4 (X)COO].sub.2 Y wherein Y represents dimethylsulfoxide, dimethylformamide or an alkanol, and wherein X can be located in any position and is OH, SH, SeH, NH.sub.2 or ##STR6## and a pharmaceutically acceptable non-aqueous carrier.
A non-aqueous neutral copper complex of the formula Cu[C.sub.6 H.sub.4 (X)COO].sub.2 Y wherein Y represents dimethylsulfoxide, and wherein X can be located in any position and is OH, SH, SeH, NH.sub.2 or ##STR9##
Dependencies are inferred from the claim text.