Vaccine for dental caries
AssigneeMerck & Co., Inc.
InventorsDennis J. Carlo, Jesse J. Jackson, Thomas H. Stoudt
Life of this patent
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Abstract
A vaccine against dental caries is prepared from capsular polysaccharides (one or more strains), of Streptococcus pneumoniae.
Claims8
A method of reducing the incidence of dental caries in a susceptible mammalian species comprising administering an effective amount of a capsular polysaccharide of S. pneumoniae type 4, 12 or 19.
An anti-caries composition consisting essentially of at least two capsular polysaccharides of S. pneumoniae types 4, 12 or 19 in an anti-caries effective amount in a physiologically acceptable medium, the total amount of capsular polysaccharide in the anti-caries composition not exceeding about 100.mu.g per type and a pharmaceutically acceptable topical carrier.
Dependencies are inferred from the claim text.