Blood compatible polymers and medical devices made therefrom containing dioctyladipate plasticizer
AssigneeBaxter Travenol Laboratories, Inc.
InventorsHenry M. Gajewski, Gerald A. Grode, Paul E. Measells, Jeffrey E. Miripol
Life of this patent
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Abstract
Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable plasticizer such as di-2-ethylhexyladipate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.
Claims6
The method of storing blood which comprises placing said blood for a period of days into a flexible, hemocompatible, sterilizable, chlorine-free plastic material which contains sufficient dioctyladipate to cause a reduced plasma hemoglobin content of blood stored in contact therewith for 21 days, when compared with blood stored in contact with the same blood compatible material free of dioctyladipate.
Dependencies are inferred from the claim text.