Certain 15-epi-prostacyclins

A 15-epi compound of the formula ##STR28## wherein R.sup.1 is hydrogen or C.sub.1 -C.sub.6 alkyl;

• p is zero or an integer of 1-7;
• R.sub.1 is hydroxy, C.sub.1 -C.sub.6 alkoxy, benzyloxy, or acyloxy;
• Y is chosen from the group:
• ##STR29## R.sub.2 is hydrogen, C.sub.1 -C.sub.6 alkyl or C.sub.2 -C.sub.6 alkenyl;
• R.sub.5 is hydrogen or C.sub.1 -C.sub.6 alkyl;
• n.sub.1 and n.sub.2, whether the same or different, are zero or an integer of 1 to 6,;
• R.sub.3 and R.sub.4, whether the same or different, are hydrogen, C.sub.1 -C.sub.6 alkyl or may form a ##STR30## group with a carbon atom to which they are bound;
• X is chosen from --O-- or --S--;
• R.sub.6 is a substituent chosen from (a) C.sub.1 -C.sub.4 alkyl, (b) a C.sub.3 -C.sub.9 cycloalkyl, C.sub.3 -C.sub.9 cycloalkenyl, norbornyl, or adamantyl radical each of which radicals may be substituted by one or more C.sub.1 -C.sub.6 alkyl or C.sub.1 -C.sub.6 - alkoxy groups;
• and a pharmaceutically or veterinarily acceptable salt thereof.