Back to results
US 4,285,935 AGranted
Dehydropeptide compounds, their production and their medical use
AssigneeBayer Aktiengesellschaft
InventorsEugen Etschenberg, Haireddin Jacobi, Wolfgang Opitz
Life of this patent
Estimating the term…
Abstract
This invention relates to dehydropeptides containing a tryptophan moiety useful as tumour-resolving and/or histolytic medicaments. Also included in the invention are methods for the preparation of said dehydropeptides, compositions containing said dehydropeptides and methods for the use of said dehydropeptides and dehydropeptide compositions.
Claims15
A compound which is a dehydropeptide of the formula ##STR6## or a salt thereof, in which
- R.sub.1 denotes a hydrogen atom, an optionally substituted alkyl, alkenyl, aralkyl, aralkenyl aryl, alkoxy group or a heterocyclic ring,
- R.sub.2 denotes a phenyl radical which is optionally substituted by alkyl, aryl, alkoxy, hydroxyl, nitro, amino, acylamino or halogen,
- R.sub.3 and R.sub.4 both denote a hydrogen atom, or together denote an additional bond between the two carbon atoms,
- R.sub.5 denotes a hydroxyl group or an optionally substituted alkoxy, aralkoxy or amino group and
- n is 1 or 0,
- and in which, when R.sub.3 and R.sub.4 both denote a hydrogen atom, the centre of asymmetry C* at the substituent R.sub.3 is in the racemate form, or in the D-form or L-form.
3 more elements
Dependencies are inferred from the claim text.