D-Homopregnanes
AssigneeHoffmann-La Roche Inc.
InventorsAndor Furst, Peter Keller, Marcel Muller
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Abstract
D-Homopregnanes of the formula ##STR1## wherein X is hydrogen, Y is hydroxy or X and Y taken together denote an oxygen to carbon bond; R.sup.6 is hydrogen, R.sup.7 is hydrogen, lower alkanoylthio or aroylthio, or R.sup.6 and R.sup.7 taken together denote a carbon to carbon bond and the dotted line in the 1,2-position of the A-ring together with the corresponding solid line denotes a single or double carbon to carbon bond or a pharmaceutically acceptable basic addition salt thereof when Y is hydroxy having diuretic activity are disclosed.
Claims1
A D-homopregnane of the formula ##STR9## wherein X is hydrogen and Y is hydroxy;
- R.sup.6 is hydrogen;
- R.sup.7 is lower alkanoylthio or aroylthio;
- and the dotted line in the 1,2-position of the A-ring together with the corresponding solid line denotes a single or double carbon to carbon bond, or a pharmaceutically-acceptable basic addition salt thereof.
Dependencies are inferred from the claim text.