Process for the manufacture of 4,5-dichloro-2-(4-chlorophenoxy)phenol
AssigneeCiba-Geigy Corporation
InventorClaus D. Weis
Life of this patent
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Abstract
A process for the manufacture of 4,5-dichloro-2-(4-chlorophenoxy)phenol by selective chlorination of 2-phenoxyanisole with 3 to 5 molar equivalents of chlorine, in the temperature range between -10.degree. and +50.degree. C., preferably between 0.degree. and 30.degree. C., in a lower halogenated aliphatic hydrocarbon, a lower aliphatic nitrile, in dimethyl formamide, dimethylmethanephosphonate or methanol, preferably in dimethyl formamide, dimethylmethanephosphonate, methanol, acetonitrile, propionitrile, chloroform, methylene chloride, 1,2-dichloroethane or tetrachloroethane, and demethylation of the 4,5-dichloro-2-(4-chlorophenoxy)anisole obtained as intermediate with an acid.
Claims10
A process for the manufacture of 4,5-dichloro-2-(4-chlorophenoxy)phenol, which comprises selectively chlorinating one molar equivalent of 2-phenoxyanisole at a temperature between -10.degree. and +50.degree. C., in a lower halogenated aliphatic hydrocarbon which contains at least one hydrogen atom, a lower aliphatic nitrile, dimethyl formamide, dimethylmethanephosphonate or methanol, with about 3 to 5 molar equivalents of chlorine, and demethylating the 4,5-dichloro-2-(4-chlorophenoxy)anisole obtained as intermediate with an acid.
A process for the manufacture of 4,5-dichloro-2-(4-chlorophenoxy)anisole, wherein 1 molar equivalent of 2-phenoxyanisole is selectively chlorinated with about 3 to 5 molar equivalents of chlorine at a temperature between -10.degree. and 50.degree. C. in a lower halogenated aliphatic hydrocarbon which contains at least one hydrogen atom, a lower aliphatic nitrile, dimethyl formamide, dimethylmethanephosphonate or methanol.
Dependencies are inferred from the claim text.