3-Hydroxybenzyl compounds useful as antioxidants
AssigneeSandoz Ltd.
InventorsHans Hinsken, Horst Mayerhoefer, Wolfgang Mueller
Life of this patent
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Abstract
3-Hydroxylbenzyl compounds of formula, ##STR1## in which each of R.sub.1, R.sub.2 and R.sub.3 is a hydrocarbon group, e.g. alkyl, R.sub.4 is hydrogen or alkyl, or forms with R.sub.1 --CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 --, and Z is either an oxygen- or sulphur-containing group featuring at least one ester or amide moiety, or a disubstituted amino group, Z being bound to the rest of the molecule via the oxygen or sulphur atom, or nitrogen atom, respectively, are useful as antioxidants. Organic materials which are susceptible to the degradative effects of oxygen are treated with one or more of such compounds, e.g. by incorporation into the body of the organic material, in order to be stabilized against such effects.
Claims6
A compound of the formula ##STR74## wherein R.sub.1 is C.sub.1-18 alkyl, C.sub.5-8 cycloalkyl, C.sub.1-5 alkyl-C.sub.5-8 cycloalkyl having an aggregate of carbon atoms not exceeding 10, or unsubstituted phenyl, and
- R.sub.4 is hydrogen or C.sub.1-4 alkyl;
- or
- R.sub.1 and R.sub.4 together form --CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 --;
- each of
- R.sub.2 and R.sub.3, independently, is C.sub.1-4 alkyl or cyclohexyl, with the proviso that both R.sub.2 and R.sub.3 cannot be cyclohexyl;
- and
- Z is a group --XR.sub.5 where X is oxygen or sulphur, and R.sub.5 is a group ##STR75## where D is ##STR76## each of R.sub.7 and R.sub.9, independently, is C.sub.1-18 alkyl, C.sub.5-8 cycloalkyl, phenyl-C.sub.1-4 alkyl, unsubstituted phenyl, phenyl monosubstituted by C.sub.1-4 alkyl or phenyl disubstituted by C.sub.1-4 alkyl, R.sub.10 is hydrogen, C.sub.1-18 alkyl, C.sub.5-8 cycloalkyl, benzyl, unsubstituted phenyl, phenyl monosubstituted by C.sub.1-4 alkyl or phenyl disubstituted by C.sub.1-4 alkyl, and R.sub.11 is C.sub.1-8 alkyl or phenyl.
Dependencies are inferred from the claim text.