Derivatives of xanthine
AssigneeBoehringer Mannheim GmbH
InventorsWalter-Gunar Friebe, Max Thiel, Wolfgang Kampe, Otto-Henning Wilhelms, Androniki Roesch
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Abstract
The present invention provides xanthine derivatives of the general formula: ##STR1## wherein one of the symbols R.sub.1 and R.sub.2 stands for a methyl radical and the other for a radical of the general formula: ##STR2## wherein R.sub.3 is a hydrogen atom or an acyl radical; and the pharmacologically acceptable salts thereof. The present invention also provides processes for the preparation of these compounds and pharmaceutical compositions containing them and is also concerned with the use thereof for the preparation of pharmaceutical compositions for the treatment of allergies.
Claims9
A xanthine derivative of the formula ##STR7## in which one of R.sub.1 and R.sub.2 is a methyl radical and the other a radical of the formula ##STR8## R.sub.3 is a hydrogen atom or a lower alkanoyl radical containing up to 8 carbon atoms and which can be substituted by halogen, phenyl or naphthyl, an alkenoyl radical containing up to 8 carbon atoms which can be substituted by phenyl or naphthyl, a phenyl- or alkyl-sulphonyl radical, or a C.sub.3 -C.sub.7 -cycloalkylcarbonyl, furancarbonyl, thiophenecarbonyl, pyridinocarbonyl or benzoyl radical which can be substituted by halogen, hydroxyl, C.sub.1 -C.sub.8 -alkyl, lower C.sub.1 -C.sub.8 -alkoxy, C.sub.1 -C.sub.8 -alkoxycarbonyl, C.sub.1 -C.sub.8 -alkanoyloxy, carboxyl, nitro, amino, nitrilo, trifluoromethyl, carbamoyl or benzyl,
- or a pharmacologically acceptable salt thereof.
Dependencies are inferred from the claim text.