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US 4,284,632 AGranted
3-Pyrrolin-2-one derivatives and compositions
AssigneeWarner-Lambert Company
InventorsGerhard Satzinger, Manfred F. Herrmann, Gustav Hechtfischer
Life of this patent
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Abstract
New 3-cyclicaminoalkoxy-4-phenyl-3-pyrrolin-2-ones are disclosed. These compounds exhibit anti-hypertensive and vasodilatory action.
Claims8
A compound of the formula:
- ##STR4## wherein R.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached form a saturated 5-, 6- or 7-membered heterocyclic ring which can also contain a further nitrogen atom or an oxygen or sulphur atom, A is a straight-chain or branched hydrocarbon chain containing 2 to 4 carbon atoms and R.sub.3 is a saturated or unsaturated, straight-chain or branched aliphatic hydrocarbon radical containing up to 6 carbon atoms or is the radical --Alk--Ar, wherein Alk is an alkylene chain containing up to 3 carbon atoms and Ar is a phenyl or heteroaryl radical optionally substituted by halogen atoms and/or lower alkoxy radicals;
- and the pharmacologically compatible salts thereof.
Dependencies are inferred from the claim text.