N-(2-Hydroxyethyl)-2,4,6-triiodo-3,5-bis-(2-keto-L-gulonamido)benzamide and radiological compositions containing same

A radiological composition containing N-(2-hydroxyethyl)-2,4,6-triiodo-3,5-bis-(2-keto-L-gulonamido) benzamide in a sufficient amount to provide satisfactory x-ray visualization together with a pharmaceutically acceptable radiological vehicle.

In a method for x-ray visualization wherein a radiological composition containing an x-ray contrast agent in a pharmaceutically acceptable radiological vehicle is injected in a sufficient amount to provide adequate visualization and thereafter x-ray visualization carried out, the improvement comprising utilizing as the radiological composition a composition containing N-(2-hydroxyethyl)-2,4,6-triiodo-3,5-bis-(2-keto-L-gulonamido)benzamide in a sufficient amount to provide satisfactory x-ray visualization together with a pharmaceutically acceptable radiological vehicle.

N-(2-Acetoxyethyl)-3,5-bis-(2,3:4,6-di-O-isopropyliden e-2-keto-L-gulonamido)-2,4,6-triiodobenzamide.

3,5-Bis-(2,3:4,6-di-O-isopropylidene-2-keto -L-gulonamido)-N-(2-hydroxyethyl)-2,4,6-triiodobenzamide.