IUD Arrangement
OwnerSeth T. Shaw, Jr.inventor
Life of this patent
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Abstract
An intrauterine device of the type having an external surface contacting the walls of the uterus after insertion therein, and said device having first walls defining a fluid-receiving cavity in at least a portion thereof. A concentrated fluid solution of a drug is present in the cavity and the drug is of the type providing an antifibrinolytic, an antifertility and antiproteolytic effect and is one or a mixture of more than one guanidine such as any aromatic monoguanidine, aromatic diguanidine, non-aromatic monoguanidine and non-aromatic diguanidine, and mixtures of one or more of the guanidines with one or more amidines.
Claims46
In an intrauterine device of the type insertable in the uterus and having a surface contacting the uterus and first walls defining a fluid-receiving cavity in at least a portion thereof, the improvement comprising, in combination:
- one of a concentrated fluid solution and suspension of at least one drug in said cavity and said at least one drug of the type providing an antifibrinolytic, a reversible antifertility, and an antiproteolytic effect;
- and
- said first walls of said intrauterine device comprising a polymer having a predetermined permeability to said at least one drug;
- said at least one drug comprises at least a guanidine, and
- whereby, said predetermined permeability of said first walls controls the release rate of said drug from said cavity.
In an intrauterine device of the type insertable in the uterus and having a surface contacting the uterus and first walls defining a fluid receiving cavity in at least a portion thereof, the improvement comprising, in combination:
- one of a crystalline form and a paste form of at least one drug in said cavity and said drug of the type providing an anti-fibrinolytic, reversible anti-fertility, and an anti-proteolytic effect, and
- said at least one drug comprising at least a guanidine, and
- said first walls of said intrauterine device comprising a polymer having a predetermined permeability to said drug,
- whereby said predetermined permeability of said first walls controls the release rate of said drug from said cavity.
Dependencies are inferred from the claim text.