Triiodinated aminoacetamido isophthalamide x-ray contrast agents
AssigneeSchering Corporation
InventorsUlrich Speck, Erich Klieger, Wolfgang Mutzel
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AssigneeSchering Corporation
InventorsUlrich Speck, Erich Klieger, Wolfgang Mutzel
Estimating the term…
Compounds of the formula ##STR1## wherein X is alkylene, optionally substituted by hydroxy, methoxy or amino; R.sup.1 is hydrogen or C.sub.1-4 alkyl; R.sup.2 is hydrogen, C.sub.1-4 alkyl, or C.sub.2-4 -alkyl substituted by 1-3 OH groups; R.sup.3 is hydrogen, C.sub.1-4 alkyl, or C.sub.2-4 -alkyl substituted by 1-3 OH groups; R.sup.4 is hydrogen, C.sub.1-4 -alkyl, or C.sub.2-4 -alkyl substituted by 1-3 OH groups; R.sup.5 is C.sub.2-4 -alkyl substituted by 1-3 OH groups; R.sup.6 is hydrogen, C.sub.1-4 -alkyl or C.sub.2-4 -alkyl substituted by 1-3 OH groups; and R.sup.7 is C.sub.2-4 -alkyl substituted by 1-3 OH groups, or a salt thereof with an acid are useful as opaquing agents in x-ray contrast media.
A 5-amino-2,4,6-triiodoisophthalic acid bisamide of the formula ##STR5## wherein X is C.sub.1-5 -alkylene, optionally substituted by hydroxy, methoxy or amino;
Dependencies are inferred from the claim text.