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US 4,261,990 AGranted
N-alkyleneiminoalkyl-dicarboximides as antiallergics and antiasthmatics
AssigneeCiba-Geigy Corporation
InventorRobert M. Bowman
Life of this patent
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Abstract
N-(diphenylmethoxy-mono- or bicyclic-alkyleneiminoalkyl)-dicarboximides, e.g. those of the formula ##STR1## A=aliphatic or cycloaliphatic radical R,R'=H, alkyl, halogen or CF.sub.3 R"=H or both are ethylene q=2-4 and salts thereof are antiallergics and antiasthmatics.
Claims8
A compound of the formula ##STR8## wherein each of Ph and Ph' is phenyl, unsubstituted or monosubstituted by lower alkyl, halogeno or trifluoromethyl;
- each of R.sub.1 and R.sub.2 are hydrogen, alkyl with up to 3 carbon atoms, or both (R.sub.1 +R.sub.2) together represent alkylene with up to 3 carbon atoms;
- each of m and n is an integer from 1 to 3;
- p is an integer from 2 to 7, whereby C.sub.p H.sub.2p separates the adjacent nitrogen atoms by at least 2 carbon atoms;
- and A is alkylene or alkenylene with 2-7 carbon atoms, 4 to 7 ring-membered mono- or bicyclo-alkylene or -alkenylene, or 4 to 7 ring-membered 2-spiro-cycloalkane- (ethylene or 1,3-propylene) unsubstituted or ring-substituted by up to three lower alkyls, or a therapeutically acceptable acid addition salt thereof.
1 more element
Dependencies are inferred from the claim text.