Piperidine derivatives
AssigneeRichardson-Merrell Inc.
InventorsAlbert A. Carr, Joseph E. Dolfini, George J. Wright
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Abstract
Pharmaceutically useful compounds of the following formula: ##STR1## wherein R.sub.1 represents hydrogen or hydroxy; R.sub.2 represents hydrogen; or R.sub.1 and R.sub.2 taken together form a second bond between the carbon atoms bearing R.sub.1 and R.sub.2 ; n is a positive whole integer of from 1 to 5; R.sub.3 is --CH.sub.3, --CH.sub.2 OH, --COOH or --COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; and A and B are individually hydrogen or hydroxy; with the provisos that at least one of A or B is hydrogen and one of A or B is other than hydrogen when R.sub.3 is --CH.sub.3 ; and pharmaceutically acceptable acid addition salts thereof.
Claims15
A compound of the formula ##STR11## wherein R.sub.1 is hydrogen or hydroxy;
- R.sub.2 is hydrogen;
- or R.sub.1 and R.sub.2 taken together form a second bond between the carbon atoms bearing R.sub.1 and R.sub.2 ;
- n is an integer of from 1 to 5;
- R.sub.3 is --COOH or --COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched;
- and A and B are individually hydrogen or hydroxy;
- with the proviso that at least one of A or B is hydrogen;
- and pharmaceutically acceptable acid addition salts thereof.
Dependencies are inferred from the claim text.