Use of phenoxyalkanes as precursors in penicillin V fermentation
AssigneeE. R. Squibb & Sons, Inc.
InventorsLaszlo J. Szarka, Robert W. Eltz
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Abstract
Penicillin V is prepared by culturing a penicillin-producing microorganism in a medium containing suitable sources of nitrogen, carbon and energy, and inorganic salts. One or more phenoxyalkanes of the formula ##STR1## wherein n is an integer from 6 to 13 are included within the medium as the sidechain precursor.
Claims8
The fermentative method of producing Penicillin V which comprises aerobically culturing a penicillin-producing microorganism in a medium containing a source of nitrogen, a source of carbon and energy, inorganic salts, and as the sidechain precursor one or more phenoxyalkanes of the formula ##STR7## wherein n is an integer from 6 to 13, said fermentation process being performed without the addition of phenoxyacetic or its salts to said medium, followed by the step of recovering the Penicillin V from said medium.
Dependencies are inferred from the claim text.