Compositions containing platinum

Abstract

This invention relates to platinum co-ordination compounds, to pharmaceutical compositions containing them. Examples of compositions falling within the scope of the present invention include: [Pt(II)(NR.sub. 1 R.sub.2)(NR.sub. 3 R.sub.4)-(CR.sub.5 R.sub.6)(X)(Y)] or (1) [Pt(II)(NR.sub. 1 R.sub.2)(NR.sub. 3 R.sub.4)-(CR.sub.5 R.sub.6)(CR.sub. 5 R.sub.6)(CR.sub. 7 R.sub.8)(X)(Y)] or (2) [Pt(IV)(NR.sub. 1 R.sub.2)(NR.sub. 3 R.sub.4)-(CR.sub.5 R.sub.6)(X)(Y)(Z).sub. 2 ] or (3) [Pt(IV)(NR.sub. 1 R.sub.2)(NR.sub. 3 R.sub.4)-(CR.sub.5 R.sub.6)(CR.sub. 7 R.sub.8)(X)(Y)(Z).sub. 2 ] (4) the R groups may be the same or different and are selected from H, straight-or branched-chain alkyl, aryl, alkaryl, aralkyl, alkenyl, cydoalkyl, cycloalkenyl, halogen, pseudohalogen (as hereinafter defined), hydroxy, alkoxy, aryloxy, formyl, nitro, amido, amino, sulphonic acids or salts thereof and carboxlic esters, acids and salts thereof, or, two R groups may together represent oxygen or sulphur, and X and Y are the same or different ligands and are selected from sulphate, phosphate, nitrate, carboxylate, substituted carboxylate and water and where R is not H or straight-chain alkyl, additionally halogen or pseudohalogen, and Z is halogen, or pseudohalogen or hydroxy.

Dependencies are inferred from the claim text.