Fibrous adsorbent for hemoperfusion
AssigneeKuraray Co., Ltd.
InventorsYoshio Fuchigami, Toshihide Nakashima
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Abstract
A hemoperfusion adsorbent is provided comprising a woven or knitted fibrous carbon adsorbent material having at least one coating thereon of a hydrophilic polymer. The adsorbent carbon fabric is preferably derived from a novolak-type phenolic resin. The hydrophilic polymer will preferably comprise a polymer prepared by the polymerization of at least one monomeric acrylate or methacrylate, preferably with a copolymerizable monomer containing an epoxy moiety.
Claims8
An adsorbent for hemoperfusion which comprises a woven or knitted fibrous structure of activated carbon with a bulk density of at least 0.25 g/cc, said activated carbon having been derived from a fibrous precursor selected from the group consisting of regenerated cellulose, polyacrylonitrile and a thermosetting polymer, and having at least one coating thereon of a hydrophilic, blood-compatible, film-forming copolymer prepared by polymerization of at least one monomeric acrylate or methacrylate represented by the formula:
- ##STR3## wherein R.sub.1 is hydrogen or methyl;
- and Y is a radical selected from the group consisting of --R.sub.2 --OR.sub.3 and --R.sub.2 --NR.sub.3 R.sub.3 ', wherein R.sub.2 is a divalent alkylene radical containing 2 to 3 carbon atoms or a poly (oxyalkylene) radical, and R.sub.3 and R.sub.3 ', respectively, are hydrogen or an alkyl group containing 1 to 3 carbon atoms, with a copolymerizable monomer containing an epoxy radical therein represented by the formula:
- ##STR4## wherein each of R.sub.1, R.sub.1 ', and R.sub.1 " independently is hydrogen or methyl;
- Z is a divalent radical selected from the group consisting of --COOR.sub.2 and --CH.sub.2 --OCH.sub.2 --, wherein R.sub.2 is a divalent alkylene radical containing 1 to 3 carbon atoms or a poly(oxyalkylene) radical;
- and n is 0 or 1;
- the copolymerizable monomer being present therein in the range of from 0.1 to 10% based on the weight of total monomers.
Dependencies are inferred from the claim text.