Treatment of diarrhoea and dysentery
AssigneeBurroughs Wellcome Co.
InventorSamuel Wilkinson
Life of this patent
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Abstract
Peptides, acid addition salts, salts, and pharmaceutical compositions thereof, and their use as morphine agonists, and especially Tyr.D.Met.Gly.Phe(4NO.sub.2).ProNH.sub.2 and Tyr.D-Met(O).Gly.Phe(4NO.sub.2).ProNH.sub.2 as anti-diarrhoeals and anti-tussives.
Claims6
A method for the treatment or prophylaxis of diarrhoea in a mammal comprising the administration to the mammal of a non-toxic, anti-diarrhoeal effective dose of Tyr. D-Met. Gly. Phe(4NO.sub.2).ProNH.sub.2 or a pharmaceutically acceptable acid addition salt thereof.
A method for the treatment or prophylaxis of diarrhoea in a mammal comprising the administration to the mammal of a non-toxic, anti-diarrhoeal effective dose of Tyr.D-Met(O). Gly. Phe(4NO.sub.2).ProNH.sub.2 or a pharmaceutically acceptable acid addition salt thereof.
A method for the induction of constipation in a mammal which comprises the administration to a mammal of an effective constipation induction amount of a compound H. Tyr.D-Met(O).Gly. Phe(4NO.sub.2). Pro.NH.sub.2 or a pharmaceutically acceptable acid addition salt thereof.
A method for the induction of constipation in a mammal which comprises the administration to a mammal of an effective constipation induction amount of the compound H. Tyr. D-Met.Gly.Phe(4NO.sub.2).Pro.NH.sub.2 or a pharmaceutically acceptable acid addition salt thereof.
A method for the treatment of dysentery in a mammal which comprises the administration to a mammal of an effective dysentery treatment amount of the compound H. Tyr. D-Met. Gly.Phe(4NO.sub.2).Pro.NH.sub.2 or a pharmaceutically acceptable acid addition salt thereof.
A method for the treatment of dysentery in a mammal which comprises the administration to a mammal of an effective dysentery treatment amount of the compound H. Tyr.D-Met(O).Gly. Phe(4NO.sub.2).Pro.NH.sub.2 or a pharmaceutically acceptable acid addition salt thereof.
Dependencies are inferred from the claim text.