Heterocyclics useful as fungicides and fungicidal compositions thereof
AssigneeHoffmann-La Roche Inc.
InventorAlbert Pfiffner
Life of this patent
Estimating the term…
Abstract
Heterocyclic compounds characterized by the formula ##STR1## wherein R.sub.1, R.sub.3, R.sub.4, R.sub.5, R.sub.6, X and z are as hereinafter set forth, prepared, inter alia, by reacting a compound characterized by the formula ##STR2## with an amine characterized by the formula ##STR3## wherein R.sub.1, R.sub.3, R.sub.4, R.sub.5, R.sub.6, X and Y are as hereinafter set forth, are described. The end products are useful as fungicidal agents.
Claims174
A compound of the formula ##STR18## , wherein R.sub.1 and R.sub.3, independently, are hydrogen or methyl;
- R.sub.4, R.sub.5 and R.sub.6, independently, are hydrogen or alkyl of 1 to 4 carbon atoms, and two of R.sub.4, R.sub.5 and R.sub.6 can each be bonded to the same carbon atom or together can form a fused alicyclic or aromatic six-membered ring;
- X is a methylene or an oxygen atom;
- z is zero or 1;
- and the dotted bonds can be hydrogenated,
- or an acid addition salt of a compound thereof which is basic.
A compound of the formula ##STR19## , wherein R.sub.1 and R.sub.3, independently, are hydrogen or methyl;
- R.sub.4, R.sub.5 and R.sub.6, independently, are hydrogen or alkyl of 1 to 4 carbon atoms, and two of R.sub.4, R.sub.5 and R.sub.6 can each be bonded to the same carbon atom or together can form a fused alicyclic or aromatic six-membered ring;
- X is a methylene or an oxygen atom;
- and the dotted bonds can be hydrogenated,
- or an acid addition salt of a compound thereof which is basic.
A compound of the formula ##STR20## , wherein R.sub.1 and R.sub.3, independently, are hydrogen or methyl;
- R.sub.4, R.sub.5 and R.sub.6, independently, are hydrogen or alkyl of 1 to 4 carbon atoms, and two of R.sub.4, R.sub.5 and R.sub.6 can each be bonded to the same carbon atom or together can form a fused alicyclic or aromatic six-membered ring;
- and X is a methylene or an oxygen atom;
- or an acid addition salt of a compound fthereof which is basic.
A compound of the formula ##STR21## wherein R.sub.1 and R.sub.3, independently, are hydrogen or methyl;
- R.sub.4, R.sub.5 and R.sub.6, independently, are hydrogen or alkyl of 1 to 4 carbon atoms, and two of R.sub.4, R.sub.5 and R.sub.6 can each be bonded to the same carbon atom or together can form a fused alicyclic or aromatic six-membered ring;
- and X is a methylene or an oxygen atom;
- or an acid addition salt of a compound thereof which is basic.
A compound of the formula ##STR22## wherein R.sub.1 and R.sub.3, independently, are hydrogen or methyl;
- R.sub.4, R.sub.5 and R.sub.6, independently, are hydrogen or alkyl of 1 to 4 carbon atoms, and two of R.sub.4, R.sub.5 and R.sub.6 can each be bonded to the same carbon atom or together can form a fused alicyclic or aromatic six-membered ring;
- and X is a methylene or an oxygen atom;
- or an acid addition salt of a compound thereof which is basic.
A compound of the formula ##STR23## wherein R.sub.1 and R.sub.3, independently, are hydrogen or methyl;
- R.sub.4, R.sub.5 and R.sub.6, independently, are hydrogen or alkyl of 1 to 4 carbon atoms, and two of R.sub.4, R.sub.5 and R.sub.6 can each be bonded to the same carbon atom or together can form a fused alicyclic or aromatic six-membered ring;
- and X is a methylene or an oxygen atom;
- or an acid addition salt of a compound thereof which is basic.
A compound of the formula ##STR24## wherein R.sub.1 and R.sub.3, independently, are hydrogen or methyl;
- R.sub.4, R.sub.5 and R.sub.6, independently, are hydrogen or alkyl of 1 to 4 carbon atoms, and two of R.sub.4, R.sub.5 and R.sub.6 can each be bonded to the same carbon atom or together can form a fused alicyclic or aromatic six-membered ring;
- and X is a methylene or an oxygen atom;
- or an acid addition salt of a compound thereof which is basic.
A compound of the formula ##STR25## wherein R.sub.1 and R.sub.3, independently, are hydrogen or methyl;
- R.sub.4, R.sub.5 and R.sub.6, independently, are hydrogen or alkyl of 1 to 4 carbon atoms, and two of R.sub.4, R.sub.5 and R.sub.6 can each be bonded to the same carbon atom or together can form a fused alicyclic or aromatic six-membered ring;
- and X is a methylene or an oxygen atom;
- or an acid addition salt of a compound thereof which is basic.
A compound of the formula ##STR26## wherein R.sub.1 and R.sub.3, independently, are hydrogen or methyl;
- R.sub.7, R.sub.8 and R.sub.9, independently, are hydrogen or methyl;
- and X is methylene or an oxygen atom,
- or an acid addition salt of a compound thereof which is basic.
A fungicidal composition comprising an effective amount of at least one compound of the formula ##STR27## wherein R.sub.1 and R.sub.3, independently, are hydrogen or methyl;
- R.sub.4, R.sub.5 and R.sub.6, independently, are hydrogen or alkyl of 1 to 4 carbon atoms, and two of R.sub.4, R.sub.5 and R.sub.6 can each be bonded to the same carbon atom or together can form a fused alicyclic or aromatic six-membered ring;
- X is a methylene or an oxygen atom;
- z is zero or 1;
- and the dotted bonds can be hydrogenated,
- or an acid addition salt of a compound thereof which is basic and an inert carrier material.
A compound of the formula ##STR28## wherein R.sub.1 and R.sub.3, independently, are hydrogen or methyl;
- R.sub.4, R.sub.5 and R.sub.6, independently, are hydrogen or alkyl of 1 to 4 carbon atoms;
- and the acid addition salts thereof.
Dependencies are inferred from the claim text.