Back to results
US 4,233,454 AGranted
Cyclopentane acetic acid derivatives
AssigneeImperial Chemical Industries PLC
InventorKeith B. Mallion
Life of this patent
Estimating the term…
Abstract
The disclosure relates to a novel sequence of reactions for manufacturing known prostaglandin intermediates, and to novel chemical intermediates obtained in the course of the novel reaction sequence, for example methyl 5.beta.-chloro-2.beta.-dimethoxymethyl-3.alpha.-hydroxycyclopent-1.alpha.- ylacetate.
Claims3
A cyclopentane derivative of the formula:
- ##STR5## wherein R.sup.2 is halogen, R.sup.4 is hydrogen or 1-4C alkyl and R.sup.5 is di(1-4Cor a radical of the formula:
- ##STR6## wherein R.sup.1 is 4-7C alkyl, phenoxymethyl or phenoxymethyl substituted in the phenyl part by halogen or trifluoromethyl, or 2-pyridyloxymethyl or 2-pyridyloxymethyl substituted in the pyridyl part by halogen.
Methyl 5.beta.-chloro-2.beta.-dimethoxymethyl-3.alpha.-hydroxycyclopent-1.alpha.- ylacetate.
5.beta. -Chloro-2.beta.-[4-(3-chlorophenoxy)-3-oxobut-1-trans-enyl]-3.alpha.-hydrox ycyclopent-1.alpha.-ylacetic acid.
Dependencies are inferred from the claim text.