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US 4,233,445 AGranted
7-(Substituted)-7H-pyrrolo[3.2-F]-quinazoline-1,3-diamines
AssigneeAmerican Home Products Corporation
InventorsKurt W. Ledig, deceased, by David R. Howes, Executor
Life of this patent
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Abstract
7-(Substituted)-pyrrolo[3,2-f]quinazoline-1,3-diamines possess antibacterial activity in vitro. The invention also provides compounds having synergism in vivo with sulfa drugs against bacterial infections.
Claims3
A compound of the general formula:
- ##STR7## or a non-toxic acid addition salt thereof, wherein:
- Y is --CH.sub.2 R or --R.sup.1
- wherein:
- R is 4-hydroxyphenyl;
- and
- R.sup.1 is 4-carbamoylphenyl.
3 more elements
Dependencies are inferred from the claim text.