Back to results
US 4,233,313 AGranted
Analgesic potentiation
AssigneeMcNeilab, Inc.
InventorJoseph F. Gardocki
Life of this patent
Estimating the term…
Abstract
A method of producing analgesia by orally administering 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid or salt thereof.
Claims2
A method for producing analgesia which comprises orally administering to a subject suffering from pain
- (1) from about 0.13 to 0.27 mg/kg of body weight of a 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid compound, said compound being selected from 1-(p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetic acid having the formula ##STR2## and (b) and therapeutically acceptable salts thereof, and (2) from about 3.8 to 7.5 mg/kg of body weight of acetaminophen.
A method for producing analgesia which comprises orally administering to a subject suffering from pain
- (1) as primary antinociceptive agent, from about 8 to 16 milligrams of 1-(p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetic acid or a non-toxic therapeutically acceptable salt thereof, and
- (2) as potentiating agent, from about 225 to 450 milligrams of acetaminophen.
Dependencies are inferred from the claim text.