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US 4,233,292 AGranted
Cyclopropyl sulfonium salts
AssigneeSandoz Ltd.
InventorFaizulla G. Kathawala
Life of this patent
Estimating the term…
Abstract
Cyclopropyl alkyl arylsulfonium salts, e.g., cyclopropyl n-propyl phenylsulfonium tetrafluoroborate, are useful as pharmaceutical agents.
Claims3
A method of treating obesity in a mammal in need of such treatment, which comprises administering to said mammal an obesity treating effective amount of a compound of the formula:
- ##STR7## wherein R is a hydrogen atom, alkyl having from 1 to 4 carbon atoms, alkoxy having from 1 to 4 carbon atoms, halo having an atomic weight of from about 19 to 35 or trifluoromethyl;
- R.sup.1 is alkyl having from 1 to 20 carbon atoms;
- and
- Z is BF.sub.4, ClO.sub.4 or SO.sub.3 R.sup.2 ;
- wherein R.sup.2 is methyl, phenyl, p-tolyl, or 2-naphthyl.
2 more elements
A pharmaceutical composition useful in treating obesity comprising in unit dosage form a pharmaceutically acceptable carrier and from 50 to 3,000 milligrams of a compound of the formula:
- ##STR8## wherein R is a hydrogen atom, alkyl having from 1 to 4 carbon atoms, alkoxy having from 1 to 4 carbon atoms, halo having an atomic weight of from about 19 to 35 or trifluoromethyl;
- R.sup.1 is alkyl having from 1 to 20 carbon atoms;
- and
- Z is BF.sub.4, ClO.sub.4 or SO.sub.3 R.sup.2 ;
- wherein R.sup.2 is methyl, phenyl, p-tolyl, or 2-naphthyl.
2 more elements
Dependencies are inferred from the claim text.