Di-Carboxylic acid derivatives
AssigneeAkzona Incorporated
InventorsAlexander C. Campbell, Colin L. Hewett, Filippus J. Zeelen
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AssigneeAkzona Incorporated
InventorsAlexander C. Campbell, Colin L. Hewett, Filippus J. Zeelen
Estimating the term…
The invention relates to novel compounds of general formula I: ##STR1## and salts, esters and amides thereof, in which R.sub.1 and R.sub.2 represent hydrogen, alkyl or alkenyl (1-4 C), R.sub.3 represents hydrogen, halogen, hydroxy, alkyl (1-4 C) or alkoxy (1-4 C), n has the value 0, 1 or 2 and ALK is a saturated or unsaturated hydrocarbon radical with 3-12 carbon atoms, in which a straight carbon chain in between the benzene rings is present, containing 3-8 carbon atoms, and the dotted line indicates an optional extra bond between the first and second carbon counted from the phenyl ring, in case of an extra bond the group R.sub.2 and one hydrogen attached to said second carbon being absent, having valuable hypocholesterolaemic and hypotriglyceriolaemic properties.
A compound of the formula:
A compound of the formula:
A pharmaceutical composition having hypocholesterolaemic and hypotriglycerolaemic properties comprising a hypotriglycerolaemically and hypocholesterolaemically effective amount of a compound of this formula:
A pharmaceutical composition having hypocholesterolaemic and hypotriglycerolaemic properties comprising a hypocholesterolaemically and hypotriglycerolaemically effective amount of a compound of the formula:
Dependencies are inferred from the claim text.