5-Alkylsulfinylbenzoyl- and 5-alkylsulfonylbenzoyl-1,2-dihydro-3H-pyrrolo[1,]pyrrole-1-carboxylic acids
AssigneeSyntex (U.S.A.) Inc.
InventorsArthur F. Kluge, Joseph M. Muchowski
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Abstract
Novel 5-alkylsulfinylbenzoyl- and 5-alkylsulfonylbenzoyl,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid compounds represented by the formula ##STR1## and the pharmaceutically acceptable, non-toxic esters and salts thereof, wherein n is 1 or 2, R is hydrogen or a lower alkyl group containing from 1-4 carbon atoms and R.sup.1 is a lower alkyl group having from 1-4 carbon atoms at the ortho, meta or para postions of the benzoyl group and process for the production of such compounds. These compounds are useful as anti-inflammatory, analgesic and antipyretic agents and as smooth muscle relaxants.
Claims19
A compound selected from the group of those represented by the formula:
- ##STR14## and the pharmaceutically acceptable, non-toxic alkyl esters having from one to 12 carbon atoms and salts thereof, wherein n is 1 or 2, R represents hydrogen or a lower alkyl group having from 1 to 4 carbon atoms and R.sup.1 represents lower alkyl group having from 1 to 4 carbon atoms at the ortho, meta or para positions of the aroyl group.
Dependencies are inferred from the claim text.