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US 4,232,026 AGranted
Diazaditwistanes, and pharmaceutical compositions for treating pain in warm blooded animals containing them
AssigneeMerck & Co., Inc.
InventorJan ten Broeke
Life of this patent
Estimating the term…
Abstract
Certain 2- and/or 9- phenylalkyl-5,11-dimethyl-5,11-diazaditwistane compounds bind to opiate receptor sites and have central nervous system activities exemplified by analgesia.
Claims7
A compound of structural formula:
- ##STR8## or a pharmaceutically acceptable salt thereof wherein:
- ##STR9##
A pharmaceutical composition for treating pain in a warm blooded animal comprising a pharmaceutical carrier and an effective amount of a compound of formula:
- ##STR12## or a pharmaceutically acceptable salt thereof, wherein:
- ##STR13##
A compound of structural formula:
- ##STR14## wherein R.sub..alpha. =-H or C.sub.1-3 alkoxy.
Dependencies are inferred from the claim text.