1-Oxo-1H-pyrimido[6,1-b]benzthiazole derivatives
AssigneeBoehringer Mannheim GmbH
InventorsWerner Winter, Herman Hindermayr, Egon Roesch, Androniki Roesch, Otto-Henning Wilhelms
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Abstract
Anti-allergy novel 1-oxo-1H-pyrimido[6,1-b]benzthiazole derivatives of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 each independently is hydrogen, halogen, hydroxy, nitro, trifluoromethyl, or lower alkyl, alkoxy or alkylthio, or R.sub.2 and R.sub.3 together are alkylenedioxy, and X is hydroxy, alkoxy or tetrazolyl-5-amino, or salts thereof, as well as their production by saponification of ##STR2## or tautomers thereof, followed by acidification.
Claims10
A 1-oxo-1H-pyrimido[6,1-b]benzthiazole of the formula ##STR8## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 each independently is hydrogen, halogen, hydroxy, nitro, trifluoromethyl, or alkyl, alkoxy or alkylthio containing up to 6 carbon atoms, or
- R.sub.2 and R.sub.3 together are alkylenedioxy containing up up to 3 carbon atoms, and
- X is hydroxy, alkoxy containing up to 6 carbon atoms or tetrazolyl-5-amino,
- or a pharmacologically acceptable salt thereof.
Dependencies are inferred from the claim text.