Antibacterial agents
AssigneeBristol-Myers Company
InventorsTakayuki Naito, Jun Okumura, Hajime Kamachi
Life of this patent
Estimating the term…
Abstract
The penicillins of the formulae ##STR1## in which R.sup.1 is phenyl, 2-thienyl, 3-thienyl, cyclohexyl, cyclohexen-1-yl, cyclohexa-1,4-dienyl, cyclohexa-1,4-dienylmethyl, 4-methoxycyclohexa-1,4-dienylmethyl or one of certain 4-substituted or 3,4-disubstituted phenyl moieties, and their pharmaceutically acceptable salts and physiologically hydrolyzed esters possess antibacterial activity and are particularly valuable in treating Pseudomonas infections.
Claims16
A compound having the formula ##STR35## or a pharmaceutically acceptable salt or conventional physiologically hydrolyzed ester thereof.
6-[D-(-)-.alpha.-Phenyl-.alpha.-(7-hydroxy-4-oxo-4H-pyr imido[1,2-b]pyridazin-3-ylcarboxamido)acetamido]penicillanic acid.
6-[D-(-)-.alpha.-(4-Hydroxyphenyl)-.alpha.-(7-h ydroxy-4-oxo-4H-pyrimido[1,2-b]pyridazin-3-ylcarboxamido)acetamido]-penicil lanic acid.
Dependencies are inferred from the claim text.