1,2,4-Triazole-3-thiols as antisecretory agents
AssigneeRichardson-Merrell Inc.
InventorsWilliam L. Albrecht, Winton D. Jones
Life of this patent
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Abstract
Compounds of the formula ##STR1## wherein R.sub.1 is H or NH.sub.2 ; R.sub.2 is C.sub.1-6 straight or branched chain alkyl; --CH.sub.2 OH; --(CH.sub.2).sub.n --O--(CH.sub.2).sub.m --CH.sub.3 ; phenyl; or --(CH.sub.2).sub.p NH.sub.2 ; n is 1-3; m is 0-3; and p is 1-5; and the pharmaceutically acceptable acid addition salts of those compounds of basic character, have antisecretory activity.
Claims5
A method of achieving antisecretory effects in a patient which comprises administering to a patient in which an antisecretory effect is desired an antisecretory amount of a compound of the formula ##STR6## wherein R.sub.1 is H or NH.sub.2 ;
- R.sub.2 is C.sub.1-6 straight or branched chain alkyl;
- --CH.sub.2 OH;
- --(CH.sub.2).sub.n --O--(CH.sub.2).sub.m --CH.sub.3 ;
- phenyl;
- or --(CH.sub.2).sub.p NH.sub.2 ;
- n is 1-3;
- m is 0-3;
- and
- p is 1-5;
- or, for those compounds of basic character, a pharmaceutically acceptable acid addition salt thereof.
Dependencies are inferred from the claim text.