Readily enterally absorbable pharmaceutical compositions of per se poorly enterally absorbable pharmacologically active agents
AssigneeKali-Chemie Pharma GmbH
InventorsTheodor Eckert, Fritz H. Kemper
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Abstract
A readily enterally absorbable pharmaceutical composition of pharmacologically active agents, which per se are poorly enterally absorbable, is disclosed which comprises a pharmacologically, effective amount of at least one such pharmacologically active agent distributed in a vehicle comprising an absorption-enhancing amount of at least one partial glyceride of a fatty acid of long chain length. The preparation is suited for formulating cardiac glycosides, steroids, or anti-capillary fragility agents.
Claims18
A readily enterally absorbable pharmaceutical composition of a per se poorly enterally absorbable pharmacologically-active agent selected from the group consisting of (1) a steroid selected from the group consisting of pregn-4-ene-3,20-dione or a pregna-4,6-diene-3,20-dione, gestagen and medrogestone and (2) an agent which is effective in improving the capillary strength comprising 2-ethyl-3-(4-hydroxybenzoyl) benzofuran, which comprises a pharmacologically effective amount of the pharmacologically-active agent distributed in a vehicle comprising an absorption enhancing amount of a glyceride selected from the group consisting of monoglycerides and diglycerides of oleic acid, stearic acid and palmitic acid and mixtures thereof.
Dependencies are inferred from the claim text.